Opioid Toxicity

Indications: Should a patient have an altered LOA and respiratory depression and suspected overdose.

Nalaxone: If the patient is ≥ 18 years of age with an altered LOA with a respiratory rate less than 10 breaths per minute and does not have an allergy or sensitivity to naloxone and is not hypoglycemic administer naloxone 0.8mg via SC or IM or IN to a maximum single dose of 0.8mg.  Repeat doses may be administered at 10 minute intervals to a maximum of 3 doses in total

If administering naloxone via IV titrate only to restore the patient’s respiratory status up to a maximum dose of 0.4mg.